Analysis on the principle of selecting plastic bottles by pharmaceutical enterprises
nowadays, there are many specifications of pharmaceutical plastic bottles, ranging from a dozen milliliters small to thousands of milliliters large, colorless and transparent, with various colors, shapes and categories. In the face of the wonderful plastic bottle market, as a pharmaceutical manufacturer, when selecting plastic bottles, it mainly grasps the following principles:
select the main raw materials of plastic bottles and the formula of additives: the product standards of plastic bottles for solid use stipulate the applicable main raw materials respectively, and they must meet the requirements of non-toxic and odor free. Since there are many main raw materials available, it is necessary to select the comprehensive properties of raw materials, Generally, tablets are made of high-density polyethylene and polypropylene bottles. If transparency is required, PET bottles can be selected. If drugs need higher barrier performance, light blocking and opaque, brown PET bottles are selected. 1. Operating procedures for electronic universal testing machine. Pen bottles have better barrier performance. Polypropylene bottles or polyester bottles are generally used as the main raw materials for liquid dosage forms
tightness and water vapor permeability of bottle body and cap. Sealing and water vapor permeability are two important technical indicators of pharmaceutical plastic bottles. They are gradually rising to be the most powerful leader of carbon fiber composite products in the future market, which plays an important role in the stability of charge
Jinan assaying tensile testing machine refers to the experimental method of measuring material properties under axial tensile load
product quality standard for plastic bottles. The quality of products can be analyzed and judged from the product quality standards of the manufacturer. Pharmaceutical plastic bottle enterprises should formulate enterprise standards that are stricter than national standards and industrial standards
quality assurance system. The audit of suppliers has become an essential part of the purchase of plastic bottles. Through the audit, we can make a comprehensive and correct assessment of the software and hardware facilities of the manufacturer, the mixing and injection of technical resin raw materials, and the comprehensive level of equipment and quality achieved through a set of special metering and injection equipment
charge stability and compatibility of plastic bottles. When selecting plastic bottles, especially new ones for new drugs, charge tests should be carried out first to investigate the stability of the charge and the compatibility between the plastic bottles and drugs. The penetration, dissolution, adsorption, chemical reaction and denaturation between drugs and plastic bottle materials must be determined through scientific testing
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