Analysis on the principle of selecting medical pla

2022-10-14
  • Detail

Analysis on the principle of selecting medical plastic bottles by enterprises

nowadays, there are many specifications of medical plastic bottles, ranging from a dozen milliliters small to thousands of milliliters large, colorless and transparent, with various colors, shapes and categories. In the face of the wonderful plastic bottle market, as a pharmaceutical manufacturer, when selecting plastic bottles, it mainly grasps the following principles:

select the main raw materials of plastic bottles and the formula of additives: the product standards of plastic bottles for solid use stipulate the applicable main raw materials respectively, and they must meet the requirements of non-toxic, non odor and so on. Since there are a variety of main raw materials available, it is necessary to select the comprehensive properties of raw materials, Generally, tablets are made of high-density polyethylene and polypropylene bottles. If it is used to measure the deformation of the sample in the process of the experiment and requires transparency, PET bottles can be selected. If drugs need higher barrier performance, light blocking and opaque, brown PET bottles can be selected, and pen bottles have better barrier performance. Polypropylene bottles or polyester bottles are generally used as the main raw materials for liquid dosage forms

tightness and water vapor permeability of bottle body and cap. Sealing and water vapor permeability are two important technical indicators of pharmaceutical plastic bottles, which have a crucial impact on the stability of the charge

product quality standards for plastic bottles. The quality of products can be analyzed and judged from the product quality standards of the manufacturer. Pharmaceutical plastic bottle enterprises should formulate enterprise standards that are stricter than national standards and industrial standards

quality assurance system. The audit of suppliers has become an essential and important link in the purchase of plastic bottles (which can also be clamped). Through the audit, the comprehensive level of software and hardware facilities, technical equipment and quality of the manufacturer can be comprehensively and correctly evaluated

charge stability and compatibility of plastic bottles. When selecting plastic bottles, especially for drugs with a newly added tariff of 25%, the loading test should be carried out first to investigate the stability of the loading and the compatibility between the plastic bottles and drugs. The penetration, dissolution, adsorption, chemical reaction and denaturation between drugs and plastic bottle materials must be determined through scientific testing

Copyright © 2011 JIN SHI